Signaling networks that convert graded stimuli into binary, all-or-none cellular responses are critical in processes ranging from cell-cycle control to lineage commitment.To exhaustively enumerate topologies that exhibit this switch-like behavior, we simulated all possible two- and three-component networks on random parameter sets, and assessed the
The article analyzes the provisions of the current criminal procedural legislation of Ukraine and separate scientific works in the field of criminal procedure regarding the detention of a person under suspicion of committing a criminal offense without a decision of the investigating judge or a court, especially when the detention of a person under
Pteropine orthoreoviruses (PRV) are emerging bat-borne viruses with proven zoonotic transmission.We recently demonstrated human exposure to PRV in Singapore, which together with previous reports from Malaysia and Vietnam suggest that human infection of PRV may occur periodically in the region.This raises the question whether bats are the only sourc